The peptides in this group are among the most intensively studied compounds affecting metabolism. They mimic the action of gut hormones and activate “switches” (receptors) in the body called GLP-1, GIP and glucagon. A receptor is the site a hormone activates to produce an effect — releasing insulin, say, or reducing appetite.
Acting on one, two or three switches
- Semaglutide — acts on one switch: GLP-1
- Tirzepatide — acts on two at once: GLP-1 and GIP
- Retatrutide — acts on three at once: GLP-1, GIP and glucagon
The research context
In the scientific literature these compounds are studied for how they affect the body's handling of fat and sugar — so far under experimental conditions (research models).
Legal note
These products are intended for in-vitro laboratory research only. They are not medicines and are not intended for use in humans.


